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Stanislaw J Czuczwar Selected Research

Ethosuximide (Zarontin)

12/2011Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice.
11/2009Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.
11/2006Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.
12/2005Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
5/2005Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
12/2004Ethosuximide and valproate display high efficacy against lindane-induced seizures in mice.
10/2004Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.
5/2003Effect of topiramate on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy.

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Stanislaw J Czuczwar Research Topics

Disease

49Seizures (Absence Seizure)
01/2018 - 06/2002
19Epilepsy (Aura)
01/2018 - 05/2003
3Drug Resistant Epilepsy
01/2017 - 10/2004
3Parkinsonian Disorders (Parkinsonism)
05/2010 - 02/2006
2Depressive Disorder (Melancholia)
11/2011 - 01/2010
2Status Epilepticus (Complex Partial Status Epilepticus)
02/2008 - 06/2007
2Ataxia (Dyssynergia)
02/2006 - 02/2006
1Alzheimer Disease (Alzheimer's Disease)
01/2012
1Mood Disorders (Mood Disorder)
01/2012
1Neuralgia (Stump Neuralgia)
01/2012
1Stroke (Strokes)
01/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2011
1Ischemia
01/2011
1Pain (Aches)
08/2009
1Lennox Gastaut Syndrome
10/2004

Drug/Important Bio-Agent (IBA)

38Anticonvulsants (Antiepileptic Drugs)IBA
01/2018 - 06/2002
17Valproic Acid (Depakote)FDA LinkGeneric
12/2011 - 10/2004
15Pentylenetetrazole (Metrazol)IBA
12/2011 - 05/2003
14Phenobarbital (Luminal)FDA Link
12/2011 - 06/2002
9Carbamazepine (Tegretol)FDA LinkGeneric
05/2009 - 06/2002
8Ethosuximide (Zarontin)FDA LinkGeneric
12/2011 - 05/2003
8Clonazepam (Rivotril)FDA LinkGeneric
12/2011 - 05/2003
7Topiramate (Topamax)FDA LinkGeneric
11/2013 - 05/2003
7Lamotrigine (Lamictal)FDA LinkGeneric
11/2013 - 08/2004
7Oxcarbazepine (Trileptal)FDA LinkGeneric
11/2013 - 04/2003
6Phenytoin (Dilantin)FDA LinkGeneric
05/2009 - 05/2003
4Gabapentin (Neurontin)FDA LinkGeneric
08/2009 - 05/2005
4VigabatrinFDA Link
03/2009 - 05/2005
3ezogabine (retigabine)IBA
01/2018 - 01/2012
3Levetiracetam (Keppra)FDA LinkGeneric
01/2015 - 03/2009
3Mesylates (Mesylate)IBA
11/2013 - 04/2011
3(3R)- ((2,3- dihydro- 5- methyl- 3- ((4- morpholinyl)methyl)pyrrolo- (1,2,3- de)- 1,4- benzoxazin- 6- yl)(1- naphthalenyl))methanone (WIN 55,212)IBA
11/2013 - 04/2011
3Pharmaceutical PreparationsIBA
01/2012 - 01/2010
3CannabinoidsIBA
12/2011 - 10/2006
3BicucullineIBA
11/2011 - 06/2007
3Pilocarpine (Ocusert)FDA LinkGeneric
11/2011 - 06/2007
3Kainic Acid (Kainate)IBA
11/2011 - 06/2007
31-methyl-1,2,3,4-tetrahydroisoquinolineIBA
05/2010 - 02/2006
3Tiagabine (Gabitril)FDA Link
08/2009 - 03/2007
3stiripentolIBA
04/2008 - 10/2006
3Felbamate (Felbatol)FDA Link
03/2005 - 08/2004
2Pregabalin (Lyrica)FDA Link
11/2013 - 05/2010
2Neurotransmitter Agents (Neurotransmitter)IBA
11/2011 - 03/2007
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
02/2008 - 06/2007
2imidazole mustard (BIC)IBA
02/2008 - 06/2007
2N-Methylaspartate (NMDA)IBA
02/2008 - 06/2007
2gamma-Aminobutyric Acid (GABA)IBA
03/2007 - 12/2004
1LacosamideFDA Link
01/2018
1Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
11/2011
1Aminophylline (Carine)FDA LinkGeneric
11/2011
1Glutamic Acid (Glutamate)FDA Link
11/2011
1Nitroarginine (NG Nitro L Arginine)IBA
11/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2011
1NicotineFDA Link
11/2011
1NeurosteroidsIBA
01/2011
1Prostaglandins BIBA
05/2010
1Milnacipran (Ixel)FDA Link
01/2010
1CoumarinsIBA
08/2009
1KetonesIBA
05/2009
1AcetoneIBA
05/2009
1osthol (osthole)IBA
04/2009
1Amiloride (Midamor)FDA LinkGeneric
01/2009
1Amlodipine (Norvasc)FDA LinkGeneric
03/2008
1Diltiazem (Cardizem)FDA LinkGeneric
03/2008
1Verapamil (Calan)FDA LinkGeneric
03/2008
1picolinic acid (chromium picolinate)IBA
02/2008
1MRZ 2-576IBA
01/2008
1imperatorinIBA
11/2007
1P-30 composite resin (P 30)IBA
08/2007
1remacemideIBA
08/2007
1isonicotinic acid benzylamideIBA
06/2007
1LigandsIBA
10/2006
1arachidonyl-2-chloroethylamideIBA
10/2006
1Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA
02/2006
1AcidsIBA
02/2006
1Dihydrotachysterol (AT 10)IBA
02/2006
1loreclezoleIBA
12/2005
1Hexachlorocyclohexane (gamma-Hexachlorocyclohexane)FDA LinkGeneric
12/2004
1Drug CombinationsIBA
04/2004
1Hormone AntagonistsIBA
01/2004
1niguldipine (dexniguldipine)IBA
06/2002

Therapy/Procedure

5Therapeutics
04/2008 - 10/2004
2Ketogenic Diet
01/2017 - 05/2009
1Subcutaneous Injections
03/2009